BERLIN — Tens of millions of people hunkered down in government-ordered isolation Tuesday as borders slammed shut, schools and businesses closed and increasingly drastic restrictions on movement took effect. Others were scrambling to get home, caught up in widespread travel restrictions that aimed to slow the spread of the new coronavirus. From Southeast Asia to Europe to the Americas, people found their lives upended by lockdowns and social distancing. Shoppers in Malaysia stood in long lines to stock up at picked-over supermarkets. Commuters in the Philippines waited in huge traffic jams at checkpoints set up to take their temperatures before entering the capital of Manila. Seven counties around San Francisco issued a sweeping shelter-in-place mandate, ordering millions to stay at home and go outside only for food, medicine and essential outings. Spain, now the fourth-most infected country, saw infections rise Tuesday by more than 2,000 in one day to 11,178 and virus-related deaths jump by almost 200 to 491. Only China, Italy and Iran had more infections. With the number of cases worldwide topping 183,000, a surge of patients in Madrid’s hospitals has fueled worries across Europe of what lies ahead. Pleas went out to send masks and ventilators to

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