A 72-year-old man in England is believed to be have had “the longest known PCR confirmed case of SARS-CoV-2 infection” after testing positive for coronavirus some 300 days. Dave Smith, of Bristol, is described in medical papers documenting his case as being immunocompromised and with a history of cancer, which may have put him at an increased risk for prolonged infection. In a preprint paper, released ahead of the July European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) conference where his case will be presented, doctors noted that the virus did not clear after a 15-day course of Remdesivir. On day 265 of his illness, he was treated with two monoclonal antibodies, casirivimab and imdevimab, and his health improved “dramatically.” Forty-five days after the treatment, the virus was not detected in RT-PCR tests. The drugs were reportedly made available to him through compassionate use and are not yet clinically approved for use in the U.K. DELTA VARIANT ON RISE IN US: WHAT TO KNOW”It is wonderful that we were able to help this individual,” Dr. Ed Moran, consultant in infectious diseases at North Bristol NHS Trust (NBT), which worked in conjunction with University of Bristol researchers, said in a news release. “Whilst


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